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Statins Reverse Doxorubicin Resistance in Mesothelioma Cells

NEW YORK JUL 12, 2006 (Reuters Health) - Statins reverse doxorubicin resistance in human malignant mesothelioma cells in culture, a finding that may lead to new clinical strategies to improve doxorubicin efficacy in this hard to treat cancer.

"The mechanism of statin-mediated inhibition of small G-protein function is the molecular basis of the drug-elicited reversion of doxorubicin resistance in human malignant mesothelioma cells," Dr. Amalia Bosia from University of Torino, Italy told Reuters Health.

Dr. Bosia and colleagues investigated the ability of statins to reverse resistance to doxorubicin in drug-resistant primary human malignant mesothelioma cells and the molecular mechanism behind the reversion, according to their report in the July 1st issue of the International Journal of Cancer.


Minority Enterprise Backer Louis Winnick, 85

Louis Winnick, 85, an economist who helped guide the investments of the Ford Foundation and promoted low-income home ownership, died July 29 at a hospice in Manhasset, Long Island.

He had mesothelioma, a type of lung cancer that his daughter Pamela Winnick attributed to exposure to asbestos when he worked in the Brooklyn Navy Yard during World War II.

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Mesothelioma Guide

Mesothelioma-Healing.com is a site designed for those who are afflicted and those whos loved one may be diagnosed with mesothelioma. The aim is to provide information that will best help someone help the one who is diagnosed with this deadly disease. Mesothelioma is a fatal cancer disease, it is best to know and understand what it is so that you may better act upon it. Ignorance is an obstacle to actions. This site provides sections that are designed to provide you with up to date information on mesothelioma. Mesothelioma-Healing also has sections that discusses the relationship between mesothelioma and asbestos and current research on mesothelioma. This website also provides legal information that helps those who may be seeking compensation and reimbursement of expensive medical expenses that may go along with mesothelioma.


Widow launches legal bid

A GRIEVING widow has launched a legal battle for £200,000 compensation after her husband died from an asbestos-related cancer.

Leslie Newman died last summer and his widow Hazel is claiming damages from Huntingdonshire District Council, which she blames for his illness and death.

Mr Newman was exposed to deadly asbestos dust and fibres when he worked at the council between 1974 and 1977.

He was diagnosed with cancer in November 2004 and died from malignant mesothelioma, a cancer of the tissues surrounding his lungs and abdomen, on June 23 2005.

Mrs Newman, of Leys Road, St Neots, brands the council negligent and in a breach of statutory duty by exposing her husband to asbestos.

She has brought he claims to London's High Court under the Fatal Accidents Act 1976 and the Law Reform Act 1934.



 

 

 

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