| Statins May Help Treat Mesothelioma
NEW YORK JUL 12, 2006 (Reuters Health) - Statins reverse doxorubicin resistance in human malignant mesothelioma cells in culture, a finding that may lead to new clinical strategies to improve doxorubicin efficacy in this hard to treat cancer. "The mechanism of statin-mediated inhibition of small G-protein function is the molecular basis of the drug-elicited reversion of doxorubicin resistance in human malignant mesothelioma cells," Dr. Amalia Bosia from University of Torino, Italy told Reuters Health. Dr. Bosia and colleagues investigated the ability of statins to reverse resistance to doxorubicin in drug-resistant primary human malignant mesothelioma cells and the molecular mechanism behind the reversion, according to their report in the July 1st issue of the International Journal of Cance Mevastatin and simvastatin significantly increased the intracellular accumulation of doxorubicin in the mesothelioma cells and increased the cytotoxicity of doxorubicin, the authors report.
Puzzling actions surround Hardie asbestos debacle
WINSTON Churchill described Russia as a riddle wrapped in a mystery inside an enigma, which can also be applied to the developing debacle around the latest attempt to coax money from James Hardie for the victims of asbestos poisoning. The riddle is the Australian Tax Office's ruling that the new entity set up by James Hardie working title: Special Purpose Fund is not a charity, thereby threatening the December deal to keep money flowing to asbestos victims. The mystery is why this fund had to be set up. Why not use the existing charity, the Medical Research and Compensation Foundation, which has been channelling compensation to James Hardie's victims? And the enigma is: why do investors think James Hardie's liability to its victims has been capped and are optimistically bidding up its share price? It has not been capped; the liability each year is limited to 35 per cent of cash flow, but the time for paying it is open-ended, and on one assessment the potential future claims are equal to the company's entire intrinsic value.
Mesothelioma Guide
Mesothelioma-Healing.com is a site designed for those who are afflicted and those whos loved one may be diagnosed with mesothelioma. The aim is to provide information that will best help someone help the one who is diagnosed with this deadly disease. Mesothelioma is a fatal cancer disease, it is best to know and understand what it is so that you may better act upon it. Ignorance is an obstacle to actions. This site provides sections that are designed to provide you with up to date information on mesothelioma. Mesothelioma-Healing also has sections that discusses the relationship between mesothelioma and asbestos and current research on mesothelioma. This website also provides legal information that helps those who may be seeking compensation and reimbursement of expensive medical expenses that may go along with mesothelioma.
Mestothelioma Cancer
Winnick died Saturday at a hospice in Manhasset, on Long Island. The cause of death was mesothelioma, a type of lung cancer that his daughter Pamela Winnick attributed to exposure to asbestos when he worked in the Brooklyn Navy Yard during World War II. Winnick was born in Romania and came to Brooklyn when he was 1. He graduated from Brooklyn College and earned a graduate degree in economics at Columbia University. He worked for the New York City Planning Commission and the Housing and Redevelopment Board before joining the Ford Foundation in 1962. He served as deputy vice president in the national affairs division from 1968 to 1986. Winnick played a major role in the foundation\'s effort to channel resources into housing, community renewal and minority enterprise following the turbulence of the late 1960s.
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